Turkey Tail Triple Extract

In the 15th century, Trametes versicolour, as a tea, was listed in the Materia Medica (Ben Cao Gang Mu) to be beneficial to the spirit (Shen), vital energy(Chi), and able to strengthen bone and tendon. Since the 1960s, extracts of Turkey Tail have been used in China and Japan for the treatment of many different cancers, gathering clinical experience as licensed medicinal products. As a result, Turkey Tail is one of the most well-researched medicinal mushrooms. Traditionally it has been used to increase circulation, for skin complaints, to help with arthritis, rheumatism, and gout. Widely distributed throughout the boreal, temperate, subtropical, and tropical regions of the world. Few mushrooms can boast such adaptivity, and variety of forms – hence the name versicolour. It is most common polypore found on dead hardwoods, more rarely on conifers.

Potential actions:

• Anti-tumour - & enhances cancer treatment - (Dan et al., 2023)
• Anti-viral - (Stamets & Wu, 2002)
• Anti-microbial - against bacterial & fungal infections - (Bains & Chawla, 2020)
• Anti-oxidant - (Kıvrak et al., 2020)
• Anti-inflammatory - (Bains & Chawla, 2020)
• Hepatoprotective (liver support) - (Stamets & Wu, 2002)
• Hypoglycaemic effects (lowering blood sugar) - (Teng et al., 2018)
• Hypolipidemic (cholesterol reducing)
• Anti-melanoma cell activity

Known compounds:

• 1,3-β-Glucans, 1,6-β-Glucans, 1,3;1,4-β-Glucans - β-Glucans
• Proteoglycans, Heteroglycans, Polysaccharide Krestin (PSK), Polysaccharide peptide (PSP - only in mycelium) - other polysaccharides
• Melanin - pigment
• Ergosterol (provitamin D2) derivatives & other sterols
• Phenolic compounds & flavonoids
• Amino acids - leucine, isoleucine, methionine, tyrosine, glutamine & asparagine
• Vitamins - B3
• Minerals - Calcium, Phosphorus, Magnesium & Iron

(Dan et al., 2023), (Stamets & Wu, 2002), (Mirre & Portela, 2016), (Kıvrak et al., 2020), (Bains & Chawla, 2020), (Teng et al., 2018)

Recommended Dosage:

1-2ml daily, either diluted in tea, coffee, water, food or taken directly from dropper to mouth. Do not exceed this.

NB. extract may lose some efficacy/bioavailability with the addition of hot temperatures (adding to hot drinks) as the final product contains a cold water portion in its ratio. So ideally taking dropper to mouth.

Research has shown Turkey Tail to benefit the following:

Cancer treatments (Nasopharyngeal, Lung, Hormone-dependent Breast, Prostate, Ovarian, Cervical, Colorectal) reducing inflammation, Influenza, Herpes, Hepatitis C, HIV, toxoplasmosis & other microbial, viral & parasitic infections. Fibromyalgia, carcinomas, side effects of radiotherapy, Arthritis, Rheumatism, Diabetes, skin allergies & abnormalities including skin pigmentary disorders.

(Dan et al., 2023), (Stamets & Wu, 2002), (Mirre & Portela, 2016), (Kıvrak et al., 2020), (Bains & Chawla, 2020), (Teng et al., 2018)

Atlantic Fungi Co-op and it’s members make no claims as to the medicinal uses of their products for specific medical conditions. These are sold as food supplements.

All suggestions on this page are our interpretation of the current scientific literature. Where research has shown positive action, it is often achieved in clinical settings. Please do your own due diligence in researching information and consulting the appropriate medical professional.

• Dan, A. et al. (2023) ‘Therapeutic effects of medicinal mushrooms on gastric, breast, and colorectal cancer: A scoping review’, Cureus [Preprint]. doi:10.7759/cureus.37574.
• Stamets, P. and Wu, Y.C.D. (2002) MycoMedicinals: An informational treatise on mushrooms. Olympia: MycoMedia.
• Mirre, J.C. and Portela, C.F. de A. (2016) 12 medicinal mushrooms. Bora, Pontevedra: Hifas da Terra.
• Kıvrak, I., Kivrak, S. and Karababa, E. (2020) ‘Assessment of bioactive compounds and antioxidant activity of Turkey tail medicinal mushroom trametes versicolor (Agaricomycetes)’, International Journal of Medicinal Mushrooms, 22(6), pp. 559–571. doi:10.1615/intjmedmushrooms.2020035027.
• Bains, A. and Chawla, P. (2020) ‘In vitro bioactivity, antimicrobial and anti-inflammatory efficacy of modified solvent evaporation assisted trametes versicolor extract’, 3 Biotech, 10(9). doi:10.1007/s13205-020-02397-w.
• Teng, J.-F. et al. (2018) ‘Potential activities and mechanisms of extracellular polysaccharopeptides from fermented trametes versicolor on regulating glucose homeostasis in insulin-resistant Hepg2 Cells’, PLOS ONE, 13(7). doi:10.1371/journal.pone.0201131.
• Habtemariam S. (2020). 'Trametes versicolor (Synn.Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy.' Biomedicines, 8(5), 135. https://doi.org/10.3390/biomedicines8050135
• Matijašević, D., Pantić, M., Rašković, B., Pavlović, V., Duvnjak, D., Sknepnek, A., & Nikšić, M. (2016). 'The Antibacterial Activity of Coriolus versicolor Methanol Extract and Its Effect on Ultrastructural Changes of Staphylococcus aureus and Salmonella Enteritidis.' Frontiers in microbiology,7, 1226. https://doi.org/10.3389/fmicb.2016.01226
• Ogbole OO, Adebisi P, Segun PA (2019). 'Medicinal mushrooms with. methicillin resistant <i>Staphylococcus aureus</i> (MRSA)inhibitory activity.' Journal of Pharmacy Bioresources. 2019;16(1):41.
• Tochikura TS, Nakashima H, Yamamoto N. 'Antiviral agents with activity against human retroviruses.' J Acquir Immune Defic Syndr. 1989;2(5):441–7.
• Monma Y, Kawana T, Shimizu F. 'In vitro inactivation of herpes
  simplex virus by a biological response modifier.' PSK Antiviral Res.1997;35(3):131–8.
• Liu A. 'SH2D1A expression reflects activation of T and NK
  cells in cord blood lymphocytes infected with EBV and treated with the immunomodulator PSK.' Immunol Lett. 2002;80(3):181–8.
• Camilleri, E., Blundell, R., Baral,
  B. et al. 'A comprehensive review on the health benefits,
  phytochemicals, and enzymatic constituents for potential therapeutic and industrial
  applications of Turkey tail mushrooms.' Discov Appl Sci 6,
  257 (2024). https://doi.org/10.1007/s42452-024-05936-9.